Alzheimer Disease - a short history.
Alzheimer's disease, given its name after a German
psychologist Alois Alzheimer, seems to be fast growing in this
day and age. Unfortunately, symptoms like brain degeneration,
cognitive impairment, and memory loss associated with the
disease have been around for centuries.
Although Alzheimers disease history enlightens us as
to where the disease got its name, Alois Alzheimer's colleague
Emil Kraepelin, played an equally important role in identifying
this disease.
Emil Kraepelin was the one to isolate and group the symptoms
of Alzheimer's disease, thus suggesting they were unique to
this disease process. Alois Alzheimer, in turn, was the
first person to understand what was actually happening inside
the brains of Alzheimer patients.
After the identification of Alzheimer's disease by these two
men in the early twentieth century, there were not very many
advances made in better understanding Alzheimer's disease, or
effectively treating the disease. At this point, Alzheimer's
disease could only be successfully diagnosed after death, by
way of an autopsy.
Before Alois Alzheimer's and Emil Capelin’s
discoveries, patients between the ages of 45 and 65 displaying
the symptoms were labeled as suffering from "pre-senile
dementia".
The name "Alzheimer's disease" was not widely used during
the 1970's and 1980's and was generally only used for people
over the age of 65. Now that the disease can be recognized and
properly diagnosed and treated it is known that the symptoms
can begin in people as young as age 30. Alzheimer's disease in
young patients more than often have a known genetic factor,
while the disease in older patients have a number of other
factors that aid in its development.
As science and technology advanced, it has lead to a
promising new time for Alzheimer's disease patients and
researchers. The first FDA approved medication developed to
slow the Alzheimer's disease process, Cognex, was approved in
1990, and three other medications followed shortly thereafter.
These medications were used to slow cognitive impairment in
cases of mild to moderate Alzheimer's disease, by increasing
levels of acetylcholine in the patient's brain.
Currently research is being done in order to find effective
ways to prevent Alzheimer's disease from ever developing.
Hormones, such as estrogen, and anti-inflammatory drugs, such
as aspirin, have been found to have a mediating effect, but can
not totally prevent the development. Environmental factors can
also play a role in Alzheimer's disease prevention. It
has also been established that people who keep their brains
active, as well as their bodies, have a lesser risk of
developing this disease.
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